What is Glucosamine?


Cortaflex is a dietary supplement which does not rely on Chondroitin and Glucosamine.

If you go into health food shops and chemists, you will find lots of products containing Chondroitin Sulphate and Glucosamine Sulphate.

So what makes it so special? What makes it different is that it has been produced with smaller molecules, so that they are more likely to be absorbed into the areas where it is needed. It is a unique formulation of the smaller key isolates of Chondroitin and Glucosamine to make it easier for the smaller molecules to be able to pass through the tiny cell walls and into the joints.

Glucosamine is an amino sugar and is a key component of cartilage. Glucosamine works to stimulate joint function and repair. It has been proven effective in numerous scientific trials for easing osteoarthritis pain, helping in the rehabilitation of cartilage, renewing synovial fluid, and repairing joints that have been damaged from osteoarthritis.

Each person produces a certain amount of glucosamine within their bodies. When people grow older, their bodies lose the capacity to make enough glucosamine. Having enough glucosamine in your body is essential to producing the nutrients needed to stimulate the production of synovial fluid, the fluid which lubricates your cartilage and keeps your joints healthy. Without enough glucosamine, the cartilage in their weight-bearing joints, such as the hips, knees, and hands deteriorates. The cartilage then hardens and forms bone spurs, deformed joints, and limited joint movement. This is how the debilitating disease of osteoarthritis develops.

If you have never tried glucosamine, you will probably find some benefit in most glucosamine supplements. However because the molecules are really large, most supplements try and increase the concentration of glucosamine in the product to try and increase the benefit to you. What Cortaflex does is to be effective by supplementing specific amino acids and amino saccharides. These are the building blocks of glucosamine and gives the body more of a chance to create more of its own glucosamine.

"The bottom line is that there is a body of evidence supporting the efficacy of oral and intramuscular glucosamine in arthritis" University of Oxford Clinical School Information Management Services Unit

Research Study

Double-blind clinical evaluation of oral glucosamine sulphate in the basic treatment of osteoarthrosis.

The efficacy and tolerance of oral glucosamine sulphate were tested against placebo in a prospective double-blind trial in 20 out-patients with established osteoarthrosis. Two capsules of either glucosamine sulphate (250 mg) or placebo were administered 3-times daily over a period of 6 to 8 weeks. Articular pain, joint tenderness and restricted movement were semi-quantitatively scored 1 to 4 every 3 days, and individually averaged over the treatment period (overall composite score). Possible side-reactions were similarly scored upon positive questioning of the patients. Haematology, erythrocyte sedimentation rate, urine analysis and X-rays were recorded before and after treatment. Significant alleviation of symptoms was associated with the use of the active drug at the prescribed dose. Similarly, patients given glucosamine sulphate experienced earlier alleviation of symptoms compared with those who had placebo. The use of glucosamine sulphate also resulted in a significantly larger proportion of patients who experienced lessening or disappearance of symptoms within the trial period. No adverse reactions were reported by the patients treated with glucosamine, and no variation in laboratory tests was recorded.

Author: Pujalte-JM; Llavore-EP; Ylescupidez-FR
Curr-Med-Res-Opin. 1980; 7(2): 110-14

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